IALANA has taken a number of initiatives including:
- Co-founding Abolition 2000, an international network of over 2000 organizations calling for a nuclear weapons convention
- Initiating the drafting of a Model Nuclear Weapons Convention which outlines the legal, technical and political elements required for the abolition and elimination of nuclear weapons
- Working with like-minded governments on the drafting and adopting of resolutions adopted by the United Nations and working papers submitted to the Non-Proliferation Treaty Review Conferences
- Producing, with the International Physicians for the Prevention of Nuclear War, Security and Survival: The Case for a Nuclear Weapons Convention, a book which explores the nature of a Nuclear Weapons Convention and how it could be achieved
- Providing expertise to governments involved in the Middle Powers Initiative’s Article VI Forum on progress like-minded States could make in exploring, developing and implementing nuclear disarmament steps
- Strategic advice to the Mayors for Peace on how to advance their Vision 2020 for the achievement and implementation of a nuclear weapons convention